Naphthoquinone derivatives (vitamins K). Vitamin K is widely distributed in the plant world, especially in the green parts of plants - grass, leafy vegetables, cereals, etc. In spinach leaves, color, cabbage, mustard, nettle, alfalfa, carrots, tomatoes, greens, green peas, hemp, and needles is fillohinon - vitamin K, which is formed in green plants - chloroplasts - light oily substance. Fillohinonom rich black currant, mountain ash and Aronia, buckthorn, wild rose. It is also found in strawberries, raspberries, red and white currants, gooseberries, irge, hawthorn.
Vitamin K1 in fruits and root crops in much smaller amounts than in leaves. Vitamin K2 is produced by the microflora of human colon. This is a light yellow crystalline substance. Vitamins K1 and K2 - naphthoquinone derivatives, are insoluble in water, soluble in oils and organic solvents. Vitamin K2 is selected from the fish meal. The complex of vitamin K is formed by many beneficial bacteria such as Escherichia coli, some of it is contained in animal products - pork liver, milk, eggs, flour from rotting and fresh fish, micro-organisms. Vitamin K is resistant to heat and a reducing agent, is rapidly destroyed by sunlight and oxidizing agents.
The daily requirement for vitamin K a healthy person - 0.3-10 mg, baby - 10-15 mg. Product life of bacteria, including those contained in the intestines of animals and humans is vitamin K3 - menahinon. Natural vitamins to enter the body with plant food and partly synthesized by intestinal microflora. Vitamin is absorbed through the bile. Fillohinon and menahinon - it antigemorragicheskie substances necessary for normal blood clotting. Believe that they are used in the liver for the formation of prothrombin, stimulate the formation of other components involved in blood coagulation, primarily fibrinogen.
It is established that vitamin K contributes to the regeneration of tissues, is involved in respiration in all cells and intracellular metabolism, has analgesic properties, enhances the reduction and motility of the gastrointestinal tract. The resulting synthetic drugs - the analogues of vitamin K have a less complex structure (while retaining the basic core of natural vitamin naftohinonovogo) have a higher activity.
Vikasol - white with a yellowish white crystalline powder, odorless, readily soluble in water, it is difficult - in alcohol. Vikasol is a specific remedy for bleeding associated with a low content of prothrombin in the blood (gipoprotrombinemii). The drug can, in some cases to increase blood clotting and with normal prothrombin. Apply vikasol jaundice, delayed the flow of bile into the intestine, acute hepatitis, parenchymal and capillary, nasal, pulmonary (tuberculosis), uterine, juvenile, ireklimaktericheskih, hemorrhoids, ulcers (gastric ulcer and duodenal ulcer) bleeding, thrombocytopenic purpura in, septic diseases accompanied by hemorrhagic phenomena, severe radiation sickness and other drug administered by mouth and intramuscularly.
Contraindicated vikasol elevated blood clotting and thrombosis. Vitamin K is called protivogemorragicheskim or coagulation vitamin because it is involved in the formation of prothrombin and promotes normal blood clotting. In the absence or deficiency of vitamin K developed hemorrhagic phenomena. Hypovitaminosis or K-avitaminosis observed more frequently with obstructive jaundice (gall stones, tumors, narrowing of the bile duct, etc.), fistulas of the gallbladder, the liver parenchyma of various diseases (acute hepatitis, acute yellow atrophy). The reason for hypovitaminosis K and K-vitamin deficiency diseases may also be accompanied by malabsorption of fat gut wall (diarrhea, ulcerative colitis, dysentery, diseases of the pancreas, sprue).
Early sign of hypovitaminosis K - reducing the number of blood prothrombin (gipoprotrombinemii). As a remedy vitamin K are successfully used in some diseases of the liver (acute hepatitis, jaundice), lung, colon, hemorrhoids, especially in lung and gastrointestinal bleeding, hemorrhagic diathesis in infants in the surgical and dental practices, as well as burns, frostbite, radiation sickness, and stomach ulcers. Deficiency of vitamin K in the organism causes a decrease in the formation of prothrombin, slow blood clotting and bleeding. Vitamin K1 - fillohinon - has a coagulating, antibacterial, antimicrobial, analgesic, hemostatic, wound-healing effect. In the form of drugs to vitamins in medicine are not used.
Tags - naphthoquinone, vitamin K, vitamin K, vitamin K1 and K2, menahinon, vikasol